Screening and analysis of a Puerto Rican Amerindian Population for high throughput Genetic Epidemiology
Genetic admixture plays an important role in the genetic epidemiology of Puerto Rico. The admixture is poorly described, specifically the Amerindian component, notwithstanding its importance in deciphering the contributing factors to many disorders and diseases. This can be addressed, as part of investigation into pre-Columbian Amerindian population. Local conditions however, limit DNA preservation, leading to variable DNA. The study describes the extraction, amplification, sequencing and analysis used for screening of this indigenous Puerto Rican population.